Melanotan 2 is a synthetic cyclic analogue of alpha-melanocyte-stimulating hormone with affinity across several melanocortin receptor subtypes, supplied as a lyophilised powder. It is supplied strictly for laboratory research use only.

What research area is Melanotan 2 associated with?

Published preclinical laboratory work in this class concerns melanocortin receptor (MC1R, MC4R) binding chemistry. We supply the material only; we make no representation as to any outcome, effect, or suitability for any purpose.

Is Melanotan 2 approved for human use?

No. Melanotan 2 is not a drug, supplement, food, cosmetic, or medical device, and has no approved human or veterinary indication. It is sold strictly for in-vitro laboratory research use by qualified professionals.

What purity is Melanotan 2 supplied at, and how is it verified?

Each lot is assayed by HPLC and ships with its own lot-specific Certificate of Analysis, published in our COA registry. Purity figures are stated per lot - we do not publish a brand-wide specification in place of the actual certificate.

Melanotan 2

Cyclic melanocortin-analogue peptide, supplied for laboratory research use only.

99.42% pure on this exact lot, verified by an independent lab, not by us
Tested in the USA. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

$49/ 10mg vial

$24.50 per vial with Buy 1, Get 1 Free

Buy 1, Get 1 Free· add 2, applied automatically

99.42% pure on this exact lot, verified by an independent lab, not by us
Tested in the USA. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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All products currently listed on this site are for research purposes only.

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Proof, not promises. Every batch, tested by an outside lab.

Every batch of Melanotan 2 is tested by an outside lab before it goes on sale — not by us. The one shipping now is lot 5ST9NN: 99.42% pure by HPLC, tested by Accurate Lab Tests on 17 Sept 2026. The signed report is right here. Purity is the number the lab measured, never “at least 99” — and a batch that misses its spec never ships.

Melanotan 2 · 10mgLot 5ST9NNLive batch data

Purity99.42%

Passed

Tested by: Accurate Lab Tests
Tested on: 17 Sept 2026
Net content: 8.58 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

See all lab reports

What happens before a vial reaches you

1Made in a controlled facilityDocumented, repeatable steps for every batch.
2Purity testedAn outside lab measures it and reports the exact number.
3Identity confirmedA second test proves it is what the label says.
4Report publishedSigned, filed by lot number, and public before the vial ships.

Live batch data

Accurate Lab Tests

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot 5ST9NNVerified

Melanotan 2 10mg

HPLC purity

99.42%

Pass · Meets spec

Tested

17 Sept 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content8.58 mgPASS

HPLC Chromatogram

Main peak 99.42% · other 0.58%

Alex JohnsonPrincipal Chemist

Authentichain · Verified 45×

MC1Rpigment

MC4Rappetite / libido

Melanocortin reachmulti-receptor

How Melanotan 2 works

A melanocortin research peptide studied for flipping more than one receptor with a single molecule.

MC1Rpigment

Studied for activating MC1R, the receptor that drives melanin and skin pigment.

MC4Rappetite / libido

Investigated for MC4R, a brain receptor tied to appetite and sexual behaviour.

Melanocortin reachmulti-receptor

Researched as a versatile tool across dermatology and neuroscience for its multi-receptor reach.

For research use only. Mechanisms described reflect published research literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of Melanotan 2 we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

3 batches on record · latest tested 17 Sept 2026

All lab reportsEvery Melanotan 2 batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Dual receptor reachPreclinical

In medicinal-chemistry work, melanotan-II is characterised as a potent agonist at the human melanocortin receptors that does not discriminate between subtypes — one molecule, more than one receptor.

MC1R + MC4R · in vitro

Journal of Medicinal Chemistry 2022 · receptor pharmacology

MC1R (pigment)pigment pathwayMC4R (appetite)feeding pathway

Described as a potent, non-selective agonist across the human melanocortin receptors.

Appetite signalPreclinical

In mice, melanotan-2 suppressed feeding — and that suppression was blunted in animals carrying one disrupted copy of the Sim1 gene, showing the feeding effect runs through this pathway.

vs normal controls

Normal signalingfull response

Sim1 disruptedimpaired

Feeding-suppression response and PVN neuron activation reduced when signaling disrupted

Molecular Endocrinology 2006 · preclinical (mice)

POMC and body weightPreclinical

In mice, disrupting the Gpr45 gene lowered hypothalamic POMC and produced obesity — and delivering melanotan-2 into the brain suppressed that obesity in the mutant animals.

vs wild-type mice

Wild-typenormal POMC

Gpr45 knockoutreduced POMC → obese

Lower POMC expression tracked with an obese phenotype

Journal of Clinical Investigation 2016 · preclinical (mice)

Full research: Melanotan II: What the Dermatology Literature Reports