KPV is a tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of alpha-melanocyte-stimulating hormone, supplied as a lyophilised powder. It is supplied strictly for laboratory research use only.

What research area is KPV associated with?

Published preclinical laboratory work in this class concerns melanocortin-fragment and cytokine signalling chemistry in cell culture. We supply the material only; we make no representation as to any outcome, effect, or suitability for any purpose.

Is KPV approved for human use?

No. KPV is not a drug, supplement, food, cosmetic, or medical device, and has no approved human or veterinary indication. It is sold strictly for in-vitro laboratory research use by qualified professionals.

What purity is KPV supplied at, and how is it verified?

Each lot is assayed by HPLC and ships with its own lot-specific Certificate of Analysis, published in our COA registry. Purity figures are stated per lot - we do not publish a brand-wide specification in place of the actual certificate.

KPV

Alpha-MSH C-terminal tripeptide, supplied for laboratory research use only.

99.21% pure on this exact lot, verified by an independent lab, not by us
Tested in the USA. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

$69/ 10mg vial

$34.50 per vial with Buy 1, Get 1 Free

Buy 1, Get 1 Free· add 2, applied automatically

99.21% pure on this exact lot, verified by an independent lab, not by us
Tested in the USA. Ships within 1 business day, stored frozen, stable at room temperature until you mix it
Retest it at any lab. If it doesn't match our report, every dollar back

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All products currently listed on this site are for research purposes only.

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Proof, not promises. Every batch, tested by an outside lab.

Every batch of KPV is tested by an outside lab before it goes on sale — not by us. The one shipping now is lot XU9VW4: 99.21% pure by HPLC, tested by Freedom Diagnostics on 05 Oct 2026. The signed report is right here. Purity is the number the lab measured, never “at least 99” — and a batch that misses its spec never ships.

KPV · 10mgLot XU9VW4Live batch data

Purity99.21%

Passed

Tested by: Freedom Diagnostics
Tested on: 05 Oct 2026
Net content: 8.17 mg

Contaminant screens

Heavy metalsEndotoxinsMicrobialSolvents

See all lab reports

What happens before a vial reaches you

1Made in a controlled facilityDocumented, repeatable steps for every batch.
2Purity testedAn outside lab measures it and reports the exact number.
3Identity confirmedA second test proves it is what the label says.
4Report publishedSigned, filed by lot number, and public before the vial ships.

Live batch data

Freedom Diagnostics

Independent analytical lab

Certificate of Analysis

RESULT · PASS

Lot XU9VW4Verified

KPV 10mg

HPLC purity

99.21%

Pass · Meets spec

Tested

05 Oct 2026

HPLC-UV + LC-MS

Analytical results

Identity (LC-MS)ConfirmedPASS

Net content8.17 mgPASS

HPLC Chromatogram

Main peak 99.21% · other 0.79%

Alex JohnsonPrincipal Chemist

Authentichain · Verified 25×

Anti-inflammatoryNF-κB

PepT1 transportgut delivery

Immune signallingcytokine tone

How KPV works

An α-MSH-derived research peptide studied for calming inflammation with a targeted route into cells.

Anti-inflammatoryNF-κB

Studied in colitis models for easing inflammation without switching off the immune system.

PepT1 transportgut delivery

Investigated for entering cells through the PepT1 nutrient transporter, concentrating in inflamed gut lining.

Immune signallingcytokine tone

Researched for dampening the inflammatory signals that drive intestinal disease models.

For research use only. Mechanisms described reflect published research literature.

Every batch we've tested

Anyone can show you one good report. Here is every batch of KPV we have ever released, newest first, each with its own signed report. Nothing hidden, nothing cherry-picked.

4 batches on record · latest tested 05 Oct 2026

All lab reportsEvery KPV batch, on one page.The full testing history with every signed report. No login, no email wall.See all lab reports

What the studies found

Published findings on this compound, each linked to its source. Animal and lab results are context, not claims about this product.

Gut inflammationPreclinical

In a colitis mouse model, KPV loaded into colon-targeted nanoparticles reduced inflammation in the gut lining compared with untreated animals.

vs untreated colitis mice

Gastroenterology 2010 · PMID 19909746

Untreated colitissevere

KPV nanoparticlesreduced

DSS-induced colitis mouse model; magnitudes illustrate direction, not exact values.

How it gets inPreclinical

KPV was shown to enter intestinal lining cells through PepT1 — a nutrient transporter — which delivered it directly into inflamed tissue and dampened the local inflammatory response.

Control cellsbaseline inflammation

After PepT1 uptakelower

Intestinal epithelial cells and mouse colitis model; relative heights show direction.

Gastroenterology 2008 · PMID 18061177

Inflammatory signalsPreclinical

In immune-cell research, alpha-MSH-derived peptides including KPV were associated with turning down pro-inflammatory cytokine signalling.

Untreatedhigh signalling

With KPV-type peptidesuppressed

Review of immune-cell studies; directional finding, not a measured percentage.

Ann. NY Acad. Sci. 2003 · PMID 12851308

Full research: KPV: Three Amino Acids From the End of a Hormone